ApE
A plasmid Editor
by M. Wayne Davis
Download Download
OSX 10.11+ (M1 Universal)
Click the icons above to download the latest ApE (v3.1.9, February 17, 2026)
A list of updates and bug fixes.

ApE has a User Manual .

Slides from a series of presentations describing some of the features of ApE
I've started a YouTube channel with tutorial videos.

ApE is now Published.

I've made a new Default Features and Fluorescent Proteins Features libraries.

Download demo theme files for circular graphic maps.

New installs will open in inline feature mode (showing the bottom stand and features in the sequence window). If you are editing large sequences or you prefer the compact view, you can turn off inline mode in Preferences (aka Settings).

Click here to download the latest ApE for Linux.
Some Windows systems will need to temporarily disable Windows Defender to install.
Click here to make a voluntary donation in support of ApE.

Get older versions


If you think that ApE doesn't find all of the ClaI sites (or XbaI or BclI) that you KNOW are present in your sequence, turn off the Dam/Dcm methylation on your sequence and try again.
See here for more information.

Last modified: June 11, 2026